Reaction and Process Optimisation
Reaction optimisation, sometimes referred to as method development, can be a very expensive process both in terms of time and money.  Poorly optimised reactions can also be costly when transferred to large scale due to poor efficiency.  Process optimisation (study of reactions under manufacture-realistic conditions) is important to develop the correct process for the reaction to be scaled-up. Atlas is an ideal system for the study of process optimisation where together with both reaction monitoring and calorimetry, important optimisation information such as temperature, pH, FBRM, turbidity and IR (infra red analysis) can be automatically plotted and logged in real time. The Syrris Atlas system allows parallel process chemistry to be performed in fully controlled jacketed lab reactors, round bottom flasks, refluxing reactor tubes or just reaction vials.	Click here to see Atlas	Click here to see Atlas Orbit
Process Optimisation in Flow Some of the difficulties of reaction optimisation include the large amount of theoretical reaction space to investigate, the requirement for significant quantities of high cost or scarce substrates, poor scalability and the large amount of time required to perform the experimentation.  Flow chemistry has the ability to assist in all of these areas.	Click here to see the Africa flow system.	Click here to see the FRX flow system.
The Africa and FRX flow systems are ideal for reaction optimisation studies. The Africa flow system combines synthesis, analysis and liquid handling to enable the following variables to be automatically modified and the effect measured: Reaction temperature Reaction time Equivalents of substrates/reagents The reagent/catalyst For examples of reaction optimisation click on : Reaction Optimisation Example 1 Reaction Optimisation Example 2	Atlas Sodium Systems in Parallel
A schematic view of an Africa flow system for reaction optimisation:
For more information about this application area please contact us    To download application notes please register with us.	The Dolomite Centre provides design, development and manufacture of glass microfluidic devices and systems.