www.syrris.com - accelerating chemistry


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Syrris Launch Ultra Smooth Flow Chemistry Pump

Asia - new, ultra smooth flow chemistry pump


Medstere generates non-obvious alternatives to leads
Medstere - generates non-obvious alternatives to leads

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Log P determination


The partition co-efficient of an extraction system is particularly important when looking to formulate a new product.  The Syrris FLLEX system can rapidly determine log P for a range of different solvent types.

The correlation between the Africa LogP/LogD System and the traditional shake flask method is excellent.  Click here to see the J. Med. Chem paper written by Pfizer Inc.

Syrris AFRICA flow system
Click here to see the AFRICA flow system.

FRX - flow chemistry toolkit
Click here to see the FRX flow system.

The FLLEX system can be used to test different solvent pairs to determine which is the most efficient for a particular extraction by determining log P.

By changing the flow rate of the solvents into the system, different equilibration times can be tested to find the optimal separation.

Log P studies can be conducted with a system as simple as the FRX schematic below shows.

More complex systems can be used to perform multiple experiments (varying concentrations, temperatures and solvents) to fully explore a range of reaction variables.  The AFRICA system shown (right) is an example of this.

 


The FRX FLLEX


The AFRICA Log P System

For more information about this
application area please contact us   

To download application notes
please register with us.

The Dolomite centre

The Dolomite Centre provides design, development and manufacture of glass microfluidic devices and systems.