Flow Basics

The list below shows some of the reactions that have been performed on both the AFRICA and FRX systems.  Syrris are seeking applications for use with the new FRX™ flow systems - Please contact us for details.

Click here to see the AFRICA flow system.

Click here to see the FRX flow system.

Homogeneous catalysis
Suzuki reaction
Heck reaction
Grubbs metathesis

Multicomponent reactions
Passerini 3CR – click for info
Biginelli 3CR
Ugi 4CR

Deprotection chemistry
BOC deprotection
MOM deprotection and intra epoxide opening
Ester saponification

Ring formations
Grubbs metathesis
Ugi followed by ring closure
Diels Alder
1,3,4 Oxadiazole formation
Fischer indole synthesis
1,3 Thioamidozole formation

Oxidations and reductions
Borohydride reduction
Borane reduction of a heterocycle
Reductive amination
Dess Martin alcohol oxidation

General syntheses
Aldol reaction
Biphasic Schotten-Baumann
HBTU amide coupling
Elimination of an alcohol to alkene
Esterification of an alcohol
Wittig reaction
Nucleophilic aromatic substitution
SN1 reaction
Mitsunobu reaction

For AFRICA application notes click here

For more information about this
application area please contact us   

To download application notes
please register with us.

The Dolomite Centre provides design, development and manufacture of glass microfluidic devices and systems.