Flow Chemistry is proving to be a productive technology for R&D chemists. It offers the chemist a new tool to speed discovery and development. Click here to find out more about the advantages of flow.
Africa is a fully automated, flexible and easy-to-use microreactor flow system. The Africa system allows R&D chemists working in discovery and process development to accelerate compound synthesis and reaction optimization.
Africa benefits:
Walk away synthesis: Fully automated hardware is controlled by the Africa software to enable unattended runs. Reagents are injected and products are collected automatically.
Faster reactions: Increase reaction rates over 100 fold by superheating reactions significantly above reflux e.g. dichloromethane to 100°C, acetonitrile to 150°C and water to 170°C.
Cleaner reactions: Reduced impurities via excellent, reproducible reaction control and optional use of solid phase reagents/catalysts/scavengers.
Inline aqueous work-up: The Flow Liquid Liquid Extraction Module (FLLEX) enables two immiscible phases to be mixed and separated in flow, immediately following the reaction.
Online analysis: A sample of reaction mixture can be taken, diluted and analyzed by HPLC in an entirely automated fashion.
Scale-up: Production rates up to kg overnight.
|
Rapid development: Reaction time, temperature and equivalents can be rapidly varied using mg of substrate.
Reactions not possible with batch synthesis: Extremely quick reaction times, reagent additions, temperature changes and quenches are possible.
Automated blockage protection: Pressure sensors continually monitor every flow channel.
Wide temperature range: Heat reactions up to 300°C or cool down to 0°C.
Chemically resistant: Glass and PTFE/ fluoropolymer wetted parts allow the widest range of chemistry possible.
Customisable: Systems are made up of functional modules, allowing each system to accurately match the need of the application.
Safer reactions: Only small amounts of material react at any time, minimising exotherms and the quantity of any hazardous intermediates. |
Africa is is a modular product. Systems can be built up by combinations of modules enabling various levels of sophistication and price.
Click here to see the Africa systems
Click here to see the Africa modules that combile to make the systems
These modules include
To see the software click here
To download an Africa brochure go to the downloads page.
For more information or to request a demo, please see Flow Chemistry, FAQ or contact us.
